The twelfth ISUILS meeting was held at Colegio Arzobispo Fonseca, Salamanca, Spain during October 6 – 11, 2013. At the opening session, we had the honor of the presence of Dr. Ana Cuevas Badallo, Secretary General of the University of Salamanca, as Master of Ceremony, and Dr. Angela Fernandez Curto, Assistant Deputy, General Director for the Planning of Scientific and Technological Infrastructures, Ministry of Economy and Competitiveness, as a representative of Spanish Government. After Prof. Yamanouchi announced the opening of the symposium and thanked the University of Salamanca and Spanish Government for their strong support for ISUILS12, a tribute was given to the Honorary Co-chairs of the symposium, Prof. Deepak Mathur and Prof. Alfred Maquet. It was followed by nine sessions covering the wide areas of rapidly growing interdisciplinary research fields of ultrafast intense laser science. We enjoyed the presentations made by the discussion leaders and invited speakers as well as by the stimulating discussions that followed the presentations.