‘Tangles’ trigger early-stage Alzheimer’s abnormalities in neocortical networks

5 mayo 2015

A ground-breaking study has now, for the first time, characterized early-stage changes that occur inside individual, Alzheimer’s-affected cells in the intact brain. Remarkably, the study indicates that even if only a small number of cells is affected, the result is a reduction of electrical activity throughout the cerebral cortex — the area of the brain that serves as the center of higher mental function and cognition.