Patient stem cells used to make dementia-in-a-dish; help identify new treatment strategy

31 diciembre 2014

A new strategy for treating an inherited form of dementia has been identified after researchers attempted to turn stem cells derived from patients into the neurons most affected by the disease. In patient-derived stem cells carrying a mutation predisposing them to frontotemporal dementia, the scientists found a targetable defect that prevents normal neurodevelopment. These stem cells partially return to normal when the defect is corrected.