New fluorescent protein permanently marks neurons that fire

12 febrero 2015

A new tool lets scientists shine a light on an animal’s brain to permanently mark neurons that are active at a particular time. The tool — a fluorescent protein called CaMPARI — converts from green to red when calcium floods a nerve cell after the cell fires. The permanent mark frees scientists from the need to focus a microscope on the right cells at the right time to observe neuronal activity.