A clearer understanding of the origin recognition complex — a protein complex that directs DNA replication — through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/JxMacJHz7WQ/150408124642.htm
Improved understanding of protein complex offers insight into DNA replication initiation mechanism basics
8 abril 2015
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