Genetically engineered Salmonella promising as anti-cancer therapy

14 abril 2015

Genetically modified Salmonella can be used to kill cancer cells, scientists report. For years, researchers have known that certain strains of bacteria, including Salmonella enterica, can kill cancer cells. Specifically Salmonella enterica Serovar Typhimurium has been shown to not only colonize solid tumors, but also to exhibit an intrinsic antitumor effect. However, in order to use Salmonella as a weapon against cancer in humans, researchers must find a balance between allowing it to kill the cancer and be safe for the patient. This bacteria, commonly known for causing severe food poisoning, can lead to sepsis and death in humans.