Xpert MTB/RIF assay for diagnosis of pulmonary tuberculosis in children: A systematic review and meta-analysis

24 marzo 2015

Microbiological confirmation of childhood tuberculosis is rare because of the difficulty of collection of specimens, low sensitivity of smear microscopy, and poor access to culture. A new study aimed to establish summary estimates for sensitivity and specificity of the Xpert MTB/RIF assay compared with microscopy in the diagnosis of pulmonary tuberculosis in children.