When vaccines are imperfect: What math can tell us about their effects on disease propagation

20 noviembre 2014

The control of certain childhood diseases is difficult, despite high vaccination coverage in many countries. One of the possible reasons for this is ‘imperfect vaccines,’ that is, vaccines that fail either due to ‘leakiness,’ lack of effectiveness on certain individuals in a population, or shorter duration of potency. In a new article, authors use a mathematical model to determine the consequences of vaccine failure and resulting disease dynamics.