Team decodes structure of protein complex active in DNA repair

3 septiembre 2015

The multifunctional ubiquitin tweaks the activity of newly made proteins, which can influence DNA damage repair via BRCA1 and anti-inflammatory responses, scientists report. One enzyme in particular, BRCC36, removes a specific type of ubiquitin central to DNA damage repair and inflammation. But BRCC36 doesn’t act on its own. It’s part of a complex with KIAA0157. How these two work together is finally coming into focus.
http://www.sciencedaily.com/releases/2015/09/150903131412.htm

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