Study revises theory of how PTEN, a critical tumor suppressor, shuts off growth signals

9 abril 2015

New evidence contradicts prior beliefs about how the protein PTEN — one of the most important of the body’s tumor suppressors — works. Specifically, a new study shows how it is recruited to particular locations in our cells where pro-growth signals need to be shut off. This work could help scientists design more effective drugs to counteract cancer’s hallmark trait, uncontrolled cellular growth.