Single enzyme’s far-reaching influence in human biology, disease

18 junio 2015

Every cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein’s function and fate, such as when it moves from one part of a cell to another or binds to other proteins. Now, researchers have made a surprisingly simple discovery: The modification of more than 100 secreted proteins is the work of a single enzyme called Fam20C.