Sendai virus defends against a threat

15 octubre 2015

A research group demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. They examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma. Researchers are now trying to screen low molecular weight compounds for developing new anti-viral drugs.