Role of Tmem2311 defined in maintaining ciliary function

13 abril 2015

Researchers reveal how a protein linked to Meckel syndrome (MKS) and other human diseases regulates the membrane composition of cilia, finger-like projections on the surface of cells that communicate signals. MKS is a rare genetic disease characterized by kidney cysts, the presence of extra fingers and toes, and defects affecting several other organs. It is part of a class of disorders known as ciliopathies, meaning that it results from defects in the structure or function of cilia.