Research identifies novel steps in Dementia progression

23 marzo 2015

Research by biologists has identified new mechanisms potentially driving progression of an aggressive form of dementia. The researchers studied how synapses — the connections between neurons — are affected by changes in the protein CHMP2B that are linked to Frontotemporal Dementia. They uncovered mechanisms that controlled growth in synapses causing them to overgrow. These signals are normally involved in immune reactions and have not been seen to function in synapse growth previously.