Protein found to block benefits of vitamin A cancer therapy

14 agosto 2014

Retinoic acid is a form of vitamin A that is used to treat and help prevent the recurrence of a variety of cancers, but for some patients the drug is not effective. The reason for this resistance was unclear until this week when researchers demonstrated that a protein known as AEG-1 blocks the effects of retinoic acid in leukemia and liver cancer. Because AEG-1 is overexpressed in nearly every cancer, these findings could impact the care of countless cancer patients.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/KfDnvWoCMF4/140814003825.htm

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