A novel mechanism for EV71 entry mediated by its receptor SCARB2 has been reported by scientists. These findings make a significant conceptual advance in the understanding of non-enveloped virus entry, to which EV71 belongs. Enterovirus 71 (EV71) is the major causative agent of hand, foot and mouth disease in the Asia-Pacific region. Unlike other enteroviruses, EV71 can cause severe aseptic meningitis, encephalitis, myocarditis and acute flaccid paralysis, thus leading to significant fatality rates.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/Boa_YteKBIE/140718110451.htm
Novel mechanism for invasion of EV71 virus demonstrated
18 julio 2014
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