Novel drug action against solid tumors explained

11 agosto 2014

Researchers have discovered how a drug that deprives the cells of a key amino acid specifically kills cancer cells. The study describes how arginine starvation specifically kills tumor cells by a novel mechanism involving mitochondria dysfunction, reactive oxygen species generation, nuclear DNA leakage and chromatin autophagy, where leaked DNA is captured and «eaten» by giant autophagosomes.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/E7e9K30Qc64/140811151123.htm

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