New test uses human stem cells to identify dangerous side effects of drugs

9 marzo 2015

A test that uses combinations of cells from a single donor’s blood to predict whether a new drug will cause a severe immune reaction in humans has been developed by researchers. The test could avert disasters like the 2006 trial of the drug TGN1412, which led to six healthy young men being admitted to intensive care with multiple organ failure. The volunteers receiving TGN1412 experienced a catastrophic inflammatory reaction called a cytokine storm.