New study challenges link between HLA class I hyperexpression in pancreas, type 1 diabetes

6 enero 2015

The cause of type 1 diabetes remains unknown. Several studies using immunohistochemistry (IHC) have independently reported hyperexpression of human leukocyte antigen (HLA) class I on pancreatic islet cells in young patients with recent-onset type 1 diabetes. Investigators have therefore suggested that HLA hyperexpression may be an important first step in the development of type 1 diabetes. However, a new study challenges these findings .
http://feeds.sciencedaily.com/~r/sciencedaily/~3/MUx9KCp1ehQ/150106081512.htm

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