New insights could result in changes to the therapeutic strategy to combat Alzheimer’s, reduce animal testing

26 mayo 2015

A typical characteristic of the brain of an Alzheimer sufferer is the presence of insoluble Tau protein aggregates. Scientists have demonstrated that the distribution of these aggregates through the brain is facilitated by synaptic connections between brain cells. This news is highly significant because the focus is increasingly on repairing synaptic connections as a therapeutic strategy in neurodegenerative diseases such as Alzheimer’s. In fact, it is generally accepted that a loss of synaptic connections leads to a loss in cognitive skills.