
The potential of a small-molecule inhibitor of NHE3 to help reduce phosphorus absorption in patients with kidney disease has been demonstrated by two separate studies. Patients with reduced kidney function are unable to maintain normal levels of phosphorus, which can lead to hyperphosphatemia.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/UrccxZu40bQ/141202110624.htm