New drug combination shows promise for breaking breast cancer resistance

20 abril 2015

A new combination of drugs has been developed that may overcome treatment resistance and relapse in breast cancer. While most women initially respond well to hormonal treatment with drugs such as tamoxifen, many go on to develop resistance and relapse. There is evidence that this is often due to activation of the Wnt signalling pathway, a gene involved in development which fuels the growth of the tumor.