19 octubre 2015
Malaria affects millions of people worldwide. Plasmodium falciparum enolase participates in parasite invasion of host red blood cells and mosquito midgut epithelium. Anti-enolase antibodies interfere with the invasion, inhibiting parasite growth and transmission. A pentapeptide insert of parasite enolase, conserved in all Plasmodia species, but absent from host enolases, shows considerable protection against malaria when displayed on Archaeal gas vesicle nanoparticles. A vaccine based on this motif could confer protection against all malaria parasites.
http://www.sciencedaily.com/releases/2015/10/151019143353.htm
