Neurodegenerative diseases: Has a possible new lead been found?

24 noviembre 2014

Good communication between brain cells is vital for optimal (mental) health. Mutations in the TBC1D24 gene inhibit this process, thereby causing neurodegeneration and epilepsy. Fruit flies with a defect in Skywalker, the fruit fly variant of TBC1D24, are being used as a model for neurodegeneration. Researchers have succeeded in completely suppressing neurodegeneration in such fruit flies, by partially inhibiting the breakdown of ‘defective’ proteins in brain cells.