Metabolic enzyme stops progression of most common type of kidney cancer

21 julio 2014

An enzyme called FBP1 — essential for regulating metabolism — binds to a transcription factor in the nucleus of certain kidney cells and restrains energy production in the cell body, researchers report. What’s more, they determined that this enzyme is missing from all kidney tumor tissue analyzed. These tumor cells without FBP1 produce energy at a much faster rate than their non-cancer cell counterparts.