A new study reveals that DNA methylation — a mechanism that regulates gene expression — could influence the progression of structural damage to the joints and spine in ankylosing spondylitis. Study findings showed significant associations between a low methylation score and more radiographic progression of the disease, and implicated smoking in worsening of disease outcome.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/nYzcvXaUWUE/150612091828.htm
Mechanism regulating gene expression linked to bone and joint damage in ankylosing spondylitis
12 junio 2015
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