A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, researchers have found. The research potentially could lead to new therapies to treat obesity and diabetes, since the transcription factor involved – spliced X-box binding protein 1 – appears to influence the body’s sensitivity to insulin and leptin signaling.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/e2dgNuI1hNE/140725131600.htm
Manipulating key protein in brain holds potential against obesity, diabetes
25 julio 2014
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