In 2013, James E. Rothman, Randy W. Schekman, and Thomas C. Südhof won the Nobel Prize in Physiology or Medicine for their discoveries of molecular machineries for vesicle trafficking, a major transport system in cells for maintaining cellular processes. SNARE proteins are known as the minimal machinery for membrane fusion. Scientists now report that NSF/?-SNAP disassemble a single SNARE complex using various single-molecule biophysical methods that allow them to monitor and manipulate individual protein complexes.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/F_e6uB8n0ns/150327111818.htm
Long-standing mystery in membrane traffic solved
27 marzo 2015
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