
Mutations in genes that lead to childhood leukemia of the acute lymphoblastic type — the most common childhood cancer in the world — have been discovered by researchers, advancing their understanding of the disease. Currently, one in six children in the general population does not respond well to standard therapy for leukemia, and/or suffers from relapses and toxic side-effects of therapy. These figures of poor response and toxicity are even bigger among children with Down’s syndrome.
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