Key molecule in flies identified that adjusts energy use under starvation conditions

24 julio 2014

In the fly Drosophila melanogaster, p53 is activated in certain cells to adapt the metabolic response to nutrient deprivation, thus having a global effect on the organism, researchers show. The researchers also reveal the molecular mechanisms through which the activity of p53 is regulated. The results obtained in Drosophila are useful to address the study of the molecular mechanisms of p53 in vertebrate models and to examine whether this protein is involved in diabetes and obesity.