To protect future generations against genomic havoc, defects in innate defense systems usually result in sterility. In animals, the main defense against troublemaking transposons is the Piwi-interacting RNA pathway. A team has identified a protein the Piwi system uses to guide a cell’s gene-silencing machinery to the right spots in the genome, allowing it to keep transposons in check. They call the protein Panoramix, after a comic book character who endows others with great power.
http://www.sciencedaily.com/releases/2015/10/151015144717.htm
Introducing the mighty panoramix: Defender of genomes
15 octubre 2015
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