In a role reversal, RNAs proofread themselves

29 enero 2015

Building a protein is a lot like a game of telephone: information is passed along from one messenger to another, creating the potential for errors. Enzymatic machines proofread at each step, and scientists have uncovered a new quality control mechanism along this path. But in a remarkable role reversal, the proofreading isn’t done by an enzyme. Instead, one of the messengers itself has a built-in mechanism to prevent errors.