Improving tumor radiation therapy: When basic ions break DNA down

16 julio 2014

Scientists now have a better understanding of how short DNA strands decompose in microseconds. A research team found new fragmentation pathways that occur universally when DNA strands are exposed to metal ions from a family of alkaline and alkaline earth elements. These ions tend to replace protons in the DNA backbone and at the same time induce a reactive conformation leading more readily to fragmentation.