Imbalance of cellular bioenergetics in pancreatic beta-cells links to type 2 diabetes

29 julio 2015

While impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes, the cause of this dysfunction has been unknown. New research shows that in patients with type 2 diabetes, the balance between supply and demand of the mitochondrial membrane potential is altered causing a decrease in the signaling that turns on insulin secretion.img src=»http://feeds.feedburner.com/~r/sciencedaily/~4/1VqXL22VhFo» height=»1″ width=»1″ alt=»»/
http://feeds.sciencedaily.com/~r/sciencedaily/~3/1VqXL22VhFo/150729085924.htm

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