Human enzyme (CD 39) targets Achilles heel of sepsis

5 enero 2015

Scientists use mice to show that a human membrane-bound enzyme called CD39, which can clear the dangerous buildup of adenosine triphosphate from the bloodstream, significantly improves survival of mice in sepsis. «Finding a more effective treatment for sepsis would be a major step forward,» said one researcher, «since far too many people still die from overwhelming microbial infection. If CD 39 proves to be as critical a factor in humans as in mice, this is a major discovery.»