Human cells’ protein factory has an alternate operating manual: Process may help body rein in disease-fighting side effects

9 julio 2014

Working with a gene involved in HIV infection, researchers discovered some human genes have an alternate set of operating instructions written into their protein-making machinery, which can quickly alter the proteins’ contents, functions and ability to survive. The study is the first to demonstrate the phenomenon of programmed ribosomal frameshifting in a human gene. Frameshifting helps regulate the gene’s immune response, the authors report.