Gut microorganisms cause gluten-induced pathology in mouse model of celiac disease

8 octubre 2015

Investigators interested in celiac disease have wondered why only 2 to 5 percent of genetically susceptible individuals develop the disease. Attention has focused on whether environmental determinants, including gut microorganisms, contribute to the development of celiac disease. Using a humanized mouse model of gluten sensitivity, a new study has found that the gut microbiome can play an important role in the body’s response to gluten.