Genetic mechanism discovery key to controlling cell growth in the vinegar fly

19 febrero 2015

A group of researchers has described a key interaction to understanding growth control in the vinegar fly (Drosophila melanogaster). According to the study, the interaction between the transcription factor Cabut and the protein Yorkie (YAP/TAZ in humans) is necessary for tissue and organ regeneration and growth. The study could have biomedical implications as the protein Yorkie is associated with different types of cancer; to avoid the interaction between Cabut and Yorkie could be a potential therapeutic target.