Genetic connivances of digits and genitals: Formation of these embryonic structures involves action of very similar group of genes

20 noviembre 2014

During the development of mammals, the growth and organization of digits are orchestrated by Hox genes, which are activated very early in precise regions of the embryo. These ‘architect genes’ are themselves regulated by a large piece of adjacent DNA. A new study reveals that this same DNA regulatory sequence also controls the architect genes during the development of the external genitals.