Gene knockout: Loss of a gene can be compensated by another gene

22 julio 2015

New methods for modifying the genome are currently widely discussed: Using CRISPR/Cas for instance, scientists can remove parts of the genetic code of a gene, thereby knocking it out. Furthermore, there are ways to inhibit translation of a gene into a protein. Both methods have in common that they impede production of a protein and should therefore have comparable consequences for an organism. However, it has been shown that consequences can differ, after a gene is either knocked, out or only blocked. Scientist now find that additional genes compensate for a knocked out gene and either attenuate consequences or completely compensate deficits.img src=»» height=»1″ width=»1″ alt=»»/