Epigenomics analysis reveals surprising new clues to insulin resistance

5 enero 2015

In studying the cellular structure and function of insulin, a research team has uncovered previously unknown steps in the development of insulin resistance. Previous investigations of insulin resistance have focused almost exclusively on proteins and cellular functions at or near the surface of cells, where insulin binds. However, epidemiological and molecular data have suggested that events leading to insulin resistance might also take place in the nucleus, where the DNA blueprint is stored.