Knocking out one or both crucial regulatory genes caused cleft lip, skin barrier defects, and a host of other developmental problems in mice, hinting that abnormalities in these molecular pathways could underlie many birth defects that are presently not well understood.
http://www.sciencedaily.com/releases/2015/09/150915162647.htm
Disruptions of splicing proteins cause facial, skin, organ defects in young mice
15 septiembre 2015
Volver