Dialing a bespoke signal: New drug design works from outside the cell

16 marzo 2015

Exploring the fundamental mechanism by which a cell-surface receptor transmits its signal, an international team of researchers has established proof of concept for an entirely new approach to drug design. They report that a class of synthetic molecules known as diabodies can, from outside the cell, latch onto a target receptor and manipulate it in such a manner as to induce distinct and varying effects within cells and tissues.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/G9uorTotf2c/150316101907.htm

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