Ciliopathies: New insights into development

28 octubre 2014

Cilia are anchored by the basal bodies to the plasma membrane and like many other organelles must be localized to a specific position in a cell. Diseases of the sensory or motile cilia play a key role in lung diseases or diabetes. Scientists have now discovered the protein Flattop. It regulates the asymmetric positioning of cilia. Malfunctions in this process lead to different clinical phenotypes, the experts say.