Cell’s recycling center implicated in division decisions

28 julio 2014

Most cells do not divide unless there is enough oxygen present to support their offspring, but certain cancer cells and other cell types circumvent this rule. Researchers have now identified a mechanism that overrides the cells’ warning signals, enabling cancers to continue to divide even without a robust blood supply. In the process, the researchers found that lysosomes — the cell’s protein ‘recycling centers’ — help govern cell division decisions.