
A team of bioengineers is working to reduce blood clots caused by platelet activation in ventricular assist devices (VADs) implanted in advanced heart failure patients. Previously, the team re-engineered the VAD’s high-speed rotors to eliminate more than 90% of platelet activation and clotting. The current study examines the role of platelet stiffness in activation with the goal of developing treatments that would increase platelet pliability and further reduce platelet activation and clotting.
http://www.sciencedaily.com/releases/2015/10/151007125737.htm