A bulky catalyst induces pinpoint targeting on benzene to create bioactive molecules

14 abril 2015

Tuning the para position of benzene moieties is significant for creating biologically active compounds and optoelectronic materials. Yet, attaching a functional handle specifically at the para position of benzene has been challenging due to multiple reactive sites on the ring. Chemists have developed a novel iridium catalyst that enables highly para-selective borylation on benzene, leading to the rapid synthesis of drug derivatives for treating Parkinson’s disease.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/AKs6oRfxvdU/150414083716.htm

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