3D ‘organoids’ grown from patient tumors could personalize drug screening

7 mayo 2015

Three-dimensional cultures (or ‘organoids’) derived from the tumors of cancer patients closely replicate key properties of the original tumors, reveals a study. These ‘organoid’ cultures are amenable to large-scale drug screens for the detection of genetic changes associated with drug sensitivity and pave the way for personalized treatment approaches that could optimize clinical outcomes in cancer patients.