{"id":13106,"date":"2014-11-25T12:48:32","date_gmt":"2014-11-25T12:48:32","guid":{"rendered":"https:\/\/www.clpu.es\/rss_externo\/p2x3-inhibitor-shows-75-percent-reduction-in-chronic-cough-frequency\/"},"modified":"2014-11-25T12:48:32","modified_gmt":"2014-11-25T12:48:32","slug":"p2x3-inhibitor-shows-75-percent-reduction-in-chronic-cough-frequency","status":"publish","type":"rss_externo","link":"https:\/\/www.clpu.es\/en\/rss_externo\/p2x3-inhibitor-shows-75-percent-reduction-in-chronic-cough-frequency\/","title":{"rendered":"P2X3 inhibitor shows 75 percent reduction in chronic cough frequency"},"content":{"rendered":"<p>Results from a Phase 2 clinical trial have been published, demonstrating that a drug candidate &#8212; AF-219 &#8212; reduced daytime cough frequency by 75 percent compared to placebo in patients with treatment-refractory chronic cough. AF-219 is a selective, non-narcotic, orally administered P2X3 receptor antagonist targeting the mechanism by which certain nerve fibers become hyper-sensitized.<br \/><a href='http:\/\/feeds.sciencedaily.com\/~r\/sciencedaily\/~3\/af7oie85J24\/141125074832.htm' title='P2X3 inhibitor shows 75 percent reduction in chronic cough frequency' target='_blank' rel=\"noopener\">http:\/\/feeds.sciencedaily.com\/~r\/sciencedaily\/~3\/af7oie85J24\/141125074832.htm<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"class_list":["post-13106","rss_externo","type-rss_externo","status-publish","hentry","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>P2X3 inhibitor shows 75 percent reduction in chronic cough frequency - CLPU<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.clpu.es\/rss_externo\/p2x3-inhibitor-shows-75-percent-reduction-in-chronic-cough-frequency\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"P2X3 inhibitor shows 75 percent reduction in chronic cough frequency - CLPU\" \/>\n<meta property=\"og:description\" content=\"Results from a Phase 2 clinical trial have been published, demonstrating that a drug candidate &#8212; AF-219 &#8212; reduced daytime cough frequency by 75 percent compared to placebo in patients with treatment-refractory chronic cough. 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