A major hurdle in structural biology and pharmacology is growing crystals to determine the structure of the biomolecules and pharmaceuticals under study. Researchers have now observed a key step in the nucleation and growth of some protein crystals. For this, they exploited the power of in-situ real-time X-ray scattering techniques. Their study could help to gain a deeper understanding of protein crystallization and its kinetics on nanometer length scales. The researchers observed a multi-step crystallization mechanism.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/lMO25uTAzHU/150121084530.htm
Watching protein crystal nucleation in real time
21 January 2015
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